ODCs

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2 OMIM references -
2 associated genes
13 signs/symptoms

PROTEIN INTERACTIONS: 2

1 OMIM reference -
1 associated gene
No signs/symptoms info

Peripheral resistance to thyroid hormones

Charcot-Marie-Tooth disease type 2B2

THRA	(UniProt - OMIM)		MED25	(UniProt - OMIM)
THRB	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	THRA THRB	(0.63) (0.63)	MED25 MED25

Citations in the biomedical literature:

Peripheral resistance to thyroid hormones		Charcot-Marie-Tooth disease type 2B2
	Synonym(s): (no synonyms)		Synonym(s): - AR-CMT2B2 - Autosomal recessive axonal CMT4C3 - Autosomal recessive axonal Charcot-Marie-Tooth disease type 2B2

	Classification (Orphanet): - Rare endocrine disease - Rare genetic disease		Classification (Orphanet): - Rare genetic disease - Rare neurologic disease

	Classification (ICD10): - Endocrine, nutritional and metabolic diseases -		Classification (ICD10): - Diseases of the nervous system -

	Epidemiological data: (no data available)		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: adulthood Average age of death: - Type of inheritance: autosomal recessive

	External references: 2 OMIM references - No MeSH references		External references: 1 OMIM reference - 1 MeSH reference: C537991

Peripheral resistance to thyroid hormones
	Very frequent - Absent / hypotonic / flaccid abdominal wall muscles - Autosomal dominant inheritance - Coarse face - Constipation - Face / facial anomalies - Failure to thrive / difficulties for feeding in infancy / growth delay - Hepatitis / icterus / cholestasis - Hypothyroidy - Hypotonia - Large fontanelle / delayed fontanelle closure - Macroglossia / tongue protrusion / proeminent / hypertrophic - Sleep and vigilance disorders - Umbilical hernia
Charcot-Marie-Tooth disease type 2B2
(no data available)